Reporting

ASPR/CDC Mpox Vaccination Operational Planning Guide - HHS Mpox Vaccination Program

Jurisdictions should continue providing inventory and administration reporting as outlined below until all HHS distributed doses are reconciled. 

A vial can be considered used if any of the following apply:

• ​A vial is opened, even if only a single shot is administered 
  
• A vial is reserved for second doses
  
• The entire vial is unusable due to obvious damage, apparent tampering or appears adulterated in any way (e.g., particulate matter); in addition, the vial should be reported as wastage in HPOP
  

All other vials should count towards the jurisdiction’s available inventory, including vials that have been re-distributed beyond the site receiving direct shipment.

The following table displays which metrics should be captured in each reporting requirement.

Mpox Reporting Requirements

Reporting Requirement	Vials/Doses Administered	Vials Wasted	Vials Redistributed	Vials for 1st Doses	Vials for 2nd Doses
Administration (IIS or IZDL)	X (Doses)
Inventory (HPOP)	X (Vials)	X	X	X	X

Please make sure inventory data in HPOP is up to date and accurate.  

Inventory data reported in HPOP should reflect:

• All vials at sites that receive a direct shipment by site or re-distributed or aggregated by jurisdiction.
• Inventory related to the 2022 mpox outbreak response (i.e., JYNNEOS vaccine received from the USG regardless of the HHS Phase during which it was ordered/received) 
• Inventory from the primary order site that remains on-hand
• Inventory reported in vials (i.e., not cartons or doses)
  
• Please note: Inventory reporting is intended to capture the total inventory available for administration including vials for both first and second doses.

For ease of reference, the mpox vaccine inventory and wastage guidance is shown in the table below.

Mpox Vaccine Inventory and Wastage Guidance

Product Label	Authorization	Authorized For	Regimen	Vial Volume	Doses Per Vial	Max Reportable Inventory (Unopened Vials Only)	Max Reportable Wastage  (Vials Only)
JYNNEOS	FDA Approved	18+ years	0.5 mL subcutaneous	0.5 mL	1	1	1
	EUA	<18 years	0.5 mL subcutaneous	0.5 mL	1	1	1
		18+ years	0.1 mL intradermal	0.5 mL	Up to 5	1	1

Vaccine administration should be reported to the jurisdiction immunization information system (IIS) and included in quarterly routine immunization data submissions from the jurisdiction to CDC. Questions about IIS reporting can be directed to IISInfo@cdc.gov.